- Two invitations from Sunny Sedlock -


Low Dose Naltrexone Conference, October 11, 2008, Los Angeles

The Fourth Annual Low Dose Naltrexone (LDN) Conference will be held on Saturday, October 11, 2008 in Los Angeles on the Health Sciences Campus (Mayer Auditorium, Keith Administration Building) of the University of Southern California (USC).  All the details concerning the conference can be found on the LDN web site, http://www.lowdosenaltrexone.org/conf2008.htm 

Also, it is my fondest desire to raise money on behalf of the HIV/AIDS trial in Mali.  Anything you can do to assist in this matter is appreciated more than mere words could ever convey.

I hope you will join me in this effort.  I look forward to hearing from you. 
 
Aloha,
 
Sunny Sedlock
Coordinator, Fourth Annual Low Dose Naltrexone Conference
7117 Park Terrace Drive
Alexandria, VA 22307
703-998-0272 - Home Office
703-888-9412 - Cell
2002Eldo@msn.com- E-Mail
EJS11715@aol.com - E-Mail


The Mali HIV+ AIDS Initiative

http://www.lowdosenaltrexone.org/developing_nations.htm


Given the dire situation of the growing population of HIV-infected people throughout the world, this is to call your attention to a potential treatment that holds enormous promise, and to request your help. 


The generic prescription drug naltrexone, an FDA-approved opioid antagonist, has been marketed for years in the US and elsewhere for the treatment of opiate and alcohol addiction. It has now demonstrated unparalleled success, when used in a very low dose, in strengthening the immune system in hundreds of documented cases of patients with HIV/AIDS.

The safety as well as potential efficacy of LDN in preventing AIDS was first discovered by Bernard Bihari, M.D, a Harvard-trained New York physician, in 1985. Since that time Dr. Bihari has treated more than 350 patients, 94% of whom have remained HIV positive without progression into AIDS for up to 18 or more years. Many of these individuals received only LDN and some used LDN as an auxiliary to the evolving HAART medications. However, to this date no carefully designed controlled study has been done to prove the efficacy of LDN in HIV positive individuals as prevention from developing AIDS. To more deeply evaluate this hypothesis, Dr. Bihari, Dr. Abdel Kader Traoré (and other health officials at the University Hospital in Bamako), and more recently Dr. Jaquelyn McCandless, created a protocol for a controlled, non-placebo study involving 250 adult volunteers—all of whom are HIV positive but have not yet developed any AIDS symptoms. The protocol is testing the efficacy of LDN alone compared to the current HAART medications, as well as the combination of the two. The Malian government is fully supportive of this study and will provide the HAART medications needed.

With local manufacture, LDN's cost should be no more than $25.00 dollars (US) per patient per year—far less than the least costs projected for antiretroviral therapies. Importantly, LDN has the simplicity of being taken just once a day at bedtime, as compared to the complexity of the combination antiviral regimens, and is free of side effects. This, in turn, markedly eases the burden of treatment-related public health education and medical supervision. 

The implications are clear for those millions in the developing world who are already HIV positive, and who have little possibility of affording antiretroviral medication. The latest reports indicate 25% of adults who need it are getting treatment and only 6% of children. Full-scale scientific clinical trials of LDN are urgently needed. 

To fulfill the promise of LDN as a new, affordable treatment for HIV/AIDS, The Ojai Foundation, a 501(c) 3 organization devoted to education and research, is sponsoring an integrated, two-faceted HIV/AIDS initiative conducted by the University Hospital in Bamako, Mali, that will:

1) Test the efficacy of a treatment protocol for those who are HIV positive that significantly reduces their chances of developing full-blown AIDS; and

2) Reduce the rate of HIV infection by encouraging changes in the ways men and women relate that will empower women to protect their health and the health of their children.

3) To help ensure the general availability of LDN throughout the developing world, particularly in those nations unable to afford HIV/AIDS treatment for their people.

4) To gain scientific recognition of the efficacy of LDN for the treatment of HIV/AIDS in all countries.

The Ojai Foundation Africa Fund has been established to seek financial support from individual donors in the US and elsewhere in order to continue funding this project. We are certain you agree that the urgency behind this matter is great: thousands die each day in the developing world of HIV/AIDS. LDN is a drug that could prevent millions of people from sharing the same fate.




It is our goal to raise 1 million dollars on behalf of The Ojai Foundation Africa Fund. To accomplish this goal, we want to hold a celebrity gala fundraising event in October, 2008.
The event would be held in conjunction with the Fourth Annual Low Dose Naltrexone (LDN) Conference that will be held on the Health Sciences Campus of the University of Southern California (USC) in Los Angeles on October 11, 2008.

We are seeking sponsors to hold a ($10,000 per person minimum contribution) dinner with a silent auction of celebrity donated items. To do this, we need a commitment from you, to serve as a celebrity sponsor of the event. Please contact me at your earliest convenience, so that we can proceed with making arrangements for the event.


On behalf of Dr. Jacquelyn McCandless and Dr. Jack Zimmerman, thank you for your generosity of time and attention. May we, together, help save the lives of those who suffer. 



Sincerely yours,

Susan M. (Sunny) Sedlock

US Investigators

Jaquelyn McCandless, MD (Medical Consultant), Certified by the American Board of Psychiatry and Neurology, JMcCandless@prodigy.net, phone 808-775-8142

Jack Zimmerman, PhD (Communications Consultant), Co-Chair, The Ojai Foundation Board of Directors, JMZimmerman@yahoo.com, phone 808-775-8142


Mali Investigators

Prof. Abdel Kader Traoré, MD (Principal Investigator) Department of Internal Medicine, Hôpital National du Point G, Bamako, Mali

Dr. Ousmane Koita, PharmD, PhD (Co-Principal Investigator and Contact Person), Applied Molecular Biology Laboratory University of Bamako, Bamako, Mali